LRpath

Pathway Analysis using Logistic Regression
Browse Concepts
Concept Name Gene List Download
Actions of Nitric Oxide in the Heart hsa mmu rno
Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor hsa mmu rno
Activation of Src by Protein-tyrosine phosphatase alpha hsa mmu rno
Acute Myocardial Infarction hsa mmu rno
Adhesion and Diapedesis of Granulocytes hsa mmu rno
Adhesion and Diapedesis of Lymphocytes hsa mmu rno
ADP-Ribosylation Factor hsa mmu rno
Agrin in Postsynaptic Differentiation hsa mmu rno
AKAP95 role in mitosis and chromosome dynamics hsa mmu rno
AKT Signaling Pathway hsa mmu rno
ALK in cardiac myocytes hsa mmu rno
Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling hsa mmu rno
Angiotensin-converting enzyme 2 regulates heart function hsa mmu rno
Antigen Dependent B Cell Activation hsa mmu rno
Apoptotic DNA fragmentation and tissue homeostasis hsa mmu rno
Apoptotic Signaling in Response to DNA Damage hsa mmu rno
Aspirin Blocks Signaling Pathway Involved in Platelet Activation hsa mmu rno
ATM Signaling Pathway hsa mmu rno
Attenuation of GPCR Signaling hsa mmu rno
B Cell Survival Pathway hsa mmu rno
B Lymphocyte Cell Surface Molecules hsa mmu rno
BCR Signaling Pathway hsa mmu rno
Bioactive Peptide Induced Signaling Pathway hsa mmu rno
Biosynthesis of neurotransmitters hsa mmu rno
Bone Remodelling hsa mmu rno
Ca++/ Calmodulin-dependent Protein Kinase Activation hsa mmu rno
Cadmium induces DNA synthesis and proliferation in macrophages hsa mmu rno
CARM1 and Regulation of the Estrogen Receptor hsa mmu rno
Caspase Cascade in Apoptosis hsa mmu rno
CBL mediated ligand-induced downregulation of EGF receptors hsa mmu rno
CCR3 signaling in Eosinophils hsa mmu rno
CD40L Signaling Pathway hsa mmu rno
CDK Regulation of DNA Replication hsa mmu rno
Cell Cycle: G1/S Check Point hsa mmu rno
Cell Cycle: G2/M Checkpoint hsa mmu rno
Cell to Cell Adhesion Signaling hsa mmu rno
Cells and Molecules involved in local acute inflammatory response hsa mmu rno
Ceramide Signaling Pathway hsa mmu rno
Chaperones modulate interferon Signaling Pathway hsa mmu rno
Classical Complement Pathway hsa mmu rno
Complement Pathway hsa mmu rno
Control of Gene Expression by Vitamin D Receptor hsa mmu rno
Control of skeletal myogenesis by HDAC and calcium/calmodulin-dependent kinase (CaMK) hsa mmu rno
Corticosteroids and cardioprotection hsa mmu rno
CTCF: First Multivalent Nuclear Factor hsa mmu rno
CTL mediated immune response against target cells hsa mmu rno
CXCR4 Signaling Pathway hsa mmu rno
Cyclins and Cell Cycle Regulation hsa mmu rno
Cystic Fibrosis Transmembrane Conductance Regulator And Beta 2 Adrenergic Receptor Pathway hsa mmu rno
Cytokine Network hsa mmu rno
Cytokines and Inflammatory Response hsa mmu rno
D4-GDI Signaling Pathway hsa mmu rno
Dendritic cells in regulating TH1 and TH2 Development hsa mmu rno
Deregulation of CDK5 in Alzheimers Disease hsa mmu rno
Double Stranded RNA Induced Gene Expression hsa mmu rno
Downregulated of MTA-3 in ER-negative Breast Tumors hsa mmu rno
E2F1 Destruction Pathway hsa mmu rno
Effects of calcineurin in Keratinocyte Differentiation hsa mmu rno
EGF Signaling Pathway hsa mmu rno
Electron Transport Reaction in Mitochondria hsa mmu rno
Endocytotic role of NDK, Phosphins and Dynamin hsa mmu rno
Eph Kinases and ephrins support platelet aggregation hsa mmu rno
EPO Signaling Pathway hsa mmu rno
Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia hsa mmu rno
Erk1/Erk2 Mapk Signaling pathway hsa mmu rno
Erythrocyte Differentiation Pathway hsa mmu rno
Erythropoietin mediated neuroprotection through NF-kB hsa mmu rno
Eukaryotic protein translation hsa mmu rno
Extrinsic Prothrombin Activation Pathway hsa mmu rno
FAS signaling pathway ( CD95 ) hsa mmu rno
Fc Epsilon Receptor I Signaling in Mast Cells hsa mmu rno
Feeder Pathways for Glycolysis hsa mmu rno
Fibrinolysis Pathway hsa mmu rno
fl-arrestins in GPCR Desensitization hsa mmu rno
fMLP induced chemokine gene expression in HMC-1 cells hsa mmu rno
Free Radical Induced Apoptosis hsa mmu rno
Gamma-aminobutyric Acid Receptor Life Cycle hsa mmu rno
GATA3 participate in activating the Th2 cytokine genes expression hsa mmu rno
Glycolysis Pathway hsa mmu rno
Granzyme A mediated Apoptosis Pathway hsa mmu rno
Growth Hormone Signaling Pathway hsa mmu rno
Hemoglobin's Chaperone hsa mmu rno
HIV Induced T Cell Apoptosis hsa mmu rno
HIV-I Nef: negative effector of Fas and TNF hsa mmu rno
How does salmonella hijack a cell hsa mmu rno
How Progesterone Initiates Oocyte Membrane hsa mmu rno
Human Cytomegalovirus and Map Kinase Pathways hsa mmu rno
Hypoxia and p53 in the Cardiovascular system hsa mmu rno
Hypoxia-Inducible Factor in the Cardiovascular System hsa mmu rno
IGF-1 Signaling Pathway hsa mmu rno
IL 17 Signaling Pathway hsa mmu rno
IL 2 signaling pathway hsa mmu rno
IL 3 signaling pathway hsa mmu rno
IL 4 signaling pathway hsa mmu rno
IL 5 Signaling Pathway hsa mmu rno
IL 6 signaling pathway hsa mmu rno
IL-10 Anti-inflammatory Signaling Pathway hsa mmu rno
IL-2 Receptor Beta Chain in T cell Activation hsa mmu rno
IL-7 Signal Transduction hsa mmu rno
IL12 and Stat4 Dependent Signaling Pathway in Th1 Development hsa mmu rno
IL22 Soluble Receptor Signaling Pathway hsa mmu rno
Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages hsa mmu rno
Induction of apoptosis through DR3 and DR4/5 Death Receptors hsa mmu rno
Influence of Ras and Rho proteins on G1 to S Transition hsa mmu rno
Inhibition of Cellular Proliferation by Gleevec hsa mmu rno
Insulin Signaling Pathway hsa mmu rno
Integrin Signaling Pathway hsa mmu rno
Intrinsic Prothrombin Activation Pathway hsa mmu rno
Keratinocyte Differentiation hsa mmu rno
Lck and Fyn tyrosine kinases in initiation of TCR Activation hsa mmu rno
Lectin Induced Complement Pathway hsa mmu rno
Links between Pyk2 and Map Kinases hsa mmu rno
Map Kinase Inactivation of SMRT Corepressor hsa mmu rno
MAPKinase Signaling Pathway hsa mmu rno
mCalpain and friends in Cell motility hsa mmu rno
Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) hsa mmu rno
METS affect on Macrophage Differentiation hsa mmu rno
Monocyte and its Surface Molecules hsa mmu rno
mTOR Signaling Pathway hsa mmu rno
Multi-step Regulation of Transcription by Pitx2 hsa mmu rno
Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation hsa mmu rno
Nerve growth factor pathway (NGF) hsa mmu rno
Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells hsa mmu rno
NF-kB Signaling Pathway hsa mmu rno
NFAT and Hypertrophy of the heart (Transcription in the broken heart) hsa mmu rno
NFkB activation by Nontypeable Hemophilus influenzae hsa mmu rno
Nitric Oxide Signaling Pathway hsa mmu rno
NO2-dependent IL 12 Pathway in NK cells hsa mmu rno
Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells hsa mmu rno
Nuclear Receptors in Lipid Metabolism and Toxicity hsa mmu rno
Oxidative Stress Induced Gene Expression Via Nrf2 hsa mmu rno
p38 MAPK Signaling Pathway hsa mmu rno
p53 Signaling Pathway hsa mmu rno
PDGF Signaling Pathway hsa mmu rno
Pertussis toxin-insensitive CCR5 Signaling in Macrophage hsa mmu rno
Phosphoinositides and their downstream targets. hsa mmu rno
Phospholipase C-epsilon pathway hsa mmu rno
Phospholipids as signalling intermediaries hsa mmu rno
Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway hsa mmu rno
PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase hsa mmu rno
Platelet Amyloid Precursor Protein Pathway hsa mmu rno
Presenilin action in Notch and Wnt signaling hsa mmu rno
Proteasome Complex hsa mmu rno
Protein Kinase A at the Centrosome hsa mmu rno
PTEN dependent cell cycle arrest and apoptosis hsa mmu rno
Rab GTPases Mark Targets In The Endocytotic Machinery hsa mmu rno
Rac 1 cell motility signaling pathway hsa mmu rno
Ras Signaling Pathway hsa mmu rno
Ras-Independent pathway in NK cell-mediated cytotoxicity hsa mmu rno
RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage hsa mmu rno
Regulation And Function Of ChREBP in Liver hsa mmu rno
Regulation of BAD phosphorylation hsa mmu rno
Regulation of ck1/cdk5 by type 1 glutamate receptors hsa mmu rno
Regulation of eIF2 hsa mmu rno
Regulation of eIF4e and p70 S6 Kinase hsa mmu rno
Regulation of hematopoiesis by cytokines hsa mmu rno
Regulation of p27 Phosphorylation during Cell Cycle Progression hsa mmu rno
Regulation of PGC-1a hsa mmu rno
Regulation of transcriptional activity by PML hsa mmu rno
Repression of Pain Sensation by the Transcriptional Regulator DREAM hsa mmu rno
Reversal of Insulin Resistance by Leptin hsa mmu rno
Rho cell motility signaling pathway hsa mmu rno
Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation hsa mmu rno
Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility hsa mmu rno
Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy hsa mmu rno
Role of ERBB2 in Signal Transduction and Oncology hsa mmu rno
Role of Erk5 in Neuronal Survival hsa mmu rno
Role of fl-arrestins in the activation and targeting of MAP kinases hsa mmu rno
Role of MAL in Rho-Mediated Activation of SRF hsa mmu rno
Role of MEF2D in T-cell Apoptosis hsa mmu rno
Role of Mitochondria in Apoptotic Signaling hsa mmu rno
Role of nicotinic acetylcholine receptors in the regulation of apoptosis hsa mmu rno
Role of Parkin in the Ubiquitin-Proteasomal Pathway hsa mmu rno
Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration hsa mmu rno
Role of Ran in mitotic spindle regulation hsa mmu rno
Role of Tob in T-cell activation hsa mmu rno
Roles of fl-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling hsa mmu rno
Selective expression of chemokine receptors during T-cell polarization hsa mmu rno
Signal transduction through IL1R hsa mmu rno
Signaling of Hepatocyte Growth Factor Receptor hsa mmu rno
Signaling Pathway from G-Protein Families hsa mmu rno
Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway hsa mmu rno
SODD/TNFR1 Signaling Pathway hsa mmu rno
Sonic Hedgehog (Shh) Pathway hsa mmu rno
Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle hsa mmu rno
Sprouty regulation of tyrosine kinase signals hsa mmu rno
Stathmin and breast cancer resistance to antimicrotubule agents hsa mmu rno
Stress Induction of HSP Regulation hsa mmu rno
T Cell Receptor Signaling Pathway hsa mmu rno
T Cytotoxic Cell Surface Molecules hsa mmu rno
T Helper Cell Surface Molecules hsa mmu rno
TACI and BCMA stimulation of B cell immune responses. hsa mmu rno
Telomeres, Telomerase, Cellular Aging, and Immortality hsa mmu rno
TGF beta signaling pathway hsa mmu rno
Th1/Th2 Differentiation hsa mmu rno
The 4-1BB-dependent immune response hsa mmu rno
The Citric Acid Cycle hsa mmu rno
The Co-Stimulatory Signal During T-cell Activation hsa mmu rno
The IGF-1 Receptor and Longevity hsa mmu rno
The SARS-coronavirus Life Cycle hsa mmu rno
Thrombin signaling and protease-activated receptors hsa mmu rno
TNF/Stress Related Signaling hsa mmu rno
TNFR1 Signaling Pathway hsa mmu rno
TNFR2 Signaling Pathway hsa mmu rno
Toll-Like Receptor Pathway hsa mmu rno
TPO Signaling Pathway hsa mmu rno
Transcription factor CREB and its extracellular signals hsa mmu rno
Transcription Regulation by Methyltransferase of CARM1 hsa mmu rno
Trefoil Factors Initiate Mucosal Healing hsa mmu rno
Tumor Suppressor Arf Inhibits Ribosomal Biogenesis hsa mmu rno
uCalpain and friends in Cell spread hsa mmu rno
VEGF, Hypoxia, and Angiogenesis hsa mmu rno
Vitamin C in the Brain hsa mmu rno
WNT Signaling Pathway hsa mmu rno
Y branching of actin filaments hsa mmu rno



Copyright 2010 The University of Michigan
Developed under the support of the NIH/National Library of Medicine
Grant # R01 LM008106 ("Representing and Acquiring Knowledge of Genome
Regulation") and the National Center for Integrative Biomedical
Informatics (NCIBI), NIH Grant # U54 DA021519 01A1
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